Find out when your expensive brand-name drug goes generic, how much you'll save when it does, and what you can do to pay less right now — not someday.
"Januvia went generic in May 2026. Millions of patients are still paying full price — because nobody told them. That's exactly why this site exists."
The biggest, most expensive drugs in America — and when the generic versions arrive. Updated monthly with real savings estimates.
| Drug Name | What It Treats | Brand Price/mo | Est. Generic Price | You Save | When Generic | Get Price Now |
|---|---|---|---|---|---|---|
Entresto sacubitril/valsartan |
Heart failure | $620/mo | ~$40/mo | Save 94% | ✅ Available now | |
Januvia sitagliptin |
Type 2 diabetes | $490/mo | ~$25/mo | Save 95% | ✅ Available now | |
Xarelto rivaroxaban |
Blood thinner | $520/mo | ~$35/mo | Save 93% | ✅ Available now | |
Ibrance palbociclib |
Breast cancer | $14,000/mo | ~$800/mo | Save 94% | ⏳ Expected 2026 | |
Eliquis apixaban |
Blood thinner | $530/mo | ~$45/mo | Save 91% | 📅 Expected 2028 | |
Ozempic semaglutide |
Type 2 diabetes / weight | $935/mo | ~$100/mo | Save 89% | 📅 Complex — 2031+ |
Not someday when the generic arrives — right now, with the drugs you're already taking.
Before the generic. Before anything changes. These work right now with your current prescription.
GoodRx negotiates prices with pharmacies. The coupon price is often 60–80% lower than what the pharmacy charges without it. Free to use, no membership required.
Mark Cuban's pharmacy sells over 2,000 generic drugs at dramatically lower prices — often 80-90% less than retail. No insurance needed. Ships nationwide.
Almost every major brand-name drug has a patient assistance program for people who can't afford it — even people with insurance. Most families never apply because they don't know it exists.
The plan that was cheapest last year may not be cheapest this year — especially if your medications changed. The annual review window (Oct 15–Dec 7) is the only time you can switch. Use it.
Enter any drug name and see what you should actually be paying versus what retail pharmacies charge.
Enter your drug name and we'll show you the retail price, the GoodRx price, and the Cost Plus Drugs price — so you can see exactly how much you might be overpaying.
AffordableMedsPros is a sister site to WhenParentsNeedUs.com and SandwichGenerationPros.com — three free, independent resources built for family caregivers.